How quickly does SJS or TEN typically progress?

Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are severe skin reactions that are often related to medication use. The progression of these conditions typically occurs over a span of several days. Specifically, SJS often begins with flu-like symptoms, followed by the rapid onset of skin lesions and systemic involvement.

When considering the timeline, it is well-documented that the progression can occur over a period of approximately 4 days. By this time, patients can experience significant skin detachment and other serious complications. This window is critical for timely intervention, as the disease can lead to serious morbidity and mortality if not managed appropriately.

Therefore, the progression occurring over 4 days exemplifies the typical timeframe for these conditions and underscores the urgency needed in their treatment and management.