In Ranson's Criteria, what lactate dehydrogenase (LDH) level indicates severe pancreatitis?

In Ranson's Criteria, a lactate dehydrogenase (LDH) level greater than 250 IU/L is significant in determining the severity of pancreatitis. This criterion, along with others, helps clinicians assess the prognosis of a patient with acute pancreatitis. Elevated LDH levels suggest tissue necrosis and correlate with a more severe disease process.

The thresholds set by Ranson indicate that higher LDH levels are associated with increased morbidity and mortality. An LDH greater than 250 specifically points towards a more severe inflammatory response and possible complications, making it a critical marker in the initial assessment of the patient. Understanding these levels aids in clinical decision-making and helps guide further management strategies for patients with pancreatitis.