In which renal condition will you find pigmented granular casts and renal tubular epithelial cells?

Enhance your NCCPA recertification preparation. Access multiple choice questions with hints and explanations. Get ready for your exam!

The presence of pigmented granular casts and renal tubular epithelial cells is characteristic of Acute Tubular Necrosis (ATN). In ATN, damage to the renal tubules leads to the shedding of tubular epithelial cells, which can be observed in the urine. This shedding often accompanies the formation of pigmented granular casts, which are composed of protein and cellular debris derived from the damaged renal tubules.

In ATN, this process results from various insults, such as ischemia or nephrotoxins, leading to a characteristic histological appearance in the urine. The pigmented casts can often be attributed to the presence of hemoglobin or myoglobin, depending on the underlying cause of the ATN. Overall, the combination of pigmented granular casts and renal tubular epithelial cells is a strong indicator of tubular injury typical of ATN, making it the appropriate answer to the question regarding renal conditions.

Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy