What age group and gender is a typical patient with Polyarteritis nodosa?

Polyarteritis nodosa (PAN) is classified as a systemic vasculitis that generally affects medium-sized muscular arteries. The demographic most commonly associated with this condition is middle-aged males, specifically those aged between 40 and 60 years. This age group is significant because studies and clinical observations have pointed to a higher prevalence of PAN in men between these ages compared to women and younger age groups.

Additionally, while polyarteritis nodosa can potentially be seen across various age groups and in both genders, its peak incidence occurs in middle-aged individuals, aligning with the pathophysiological mechanisms involved in this type of vasculitis. The condition's association with male patients may also stem from hormonal and environmental factors that influence the development of autoimmune diseases. Hence, a male patient aged 40-60 encompasses the typical demographic profile for polyarteritis nodosa, making this selection the most representative of the condition's common presentation.