What are typical lab findings in Polyarteritis nodosa?

In polyarteritis nodosa (PAN), the typical laboratory findings include elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). These markers indicate the presence of systemic inflammation, which is a hallmark of this condition. PAN is characterized by necrotizing vasculitis affecting medium-sized muscular arteries, leading to a range of systemic symptoms, often accompanied by inflammatory parameters in laboratory tests.

An elevated ESR suggests a higher level of inflammation in the body, which is consistent with the vasculitis seen in PAN. Similarly, an elevated CRP level reflects acute inflammatory responses and further supports the diagnosis of an active inflammatory process. Therefore, the combination of elevated ESR and CRP is typical in patients suffering from this condition, helping clinicians both to diagnose and monitor disease activity.

The other options do not accurately reflect the typical laboratory findings associated with polyarteritis nodosa and would generally not present the same inflammatory picture observed in this disease.