What is a common side effect of bisphosphonates?

Esophagitis is recognized as a common side effect of bisphosphonates, a class of medications primarily used to prevent the loss of bone mass in conditions such as osteoporosis. When administered orally, bisphosphonates can irritate the esophagus, especially if the patient does not remain upright for at least 30 minutes after taking the medication or if they do not drink sufficient water with the pill. This irritation can lead to inflammation of the esophagus, known as esophagitis, which may present with symptoms such as painful swallowing, chest pain, or heartburn.

In contrast, the other side effects listed, such as dizziness, nausea, and headache, may occur but are not considered as common or direct consequences of bisphosphonate use. Understanding the specific risks associated with bisphosphonates is crucial for patients and healthcare providers to ensure safe administration and minimize complications.