What is the most common preexisting infection associated with periorbital cellulitis?

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Periorbital cellulitis, an infection of the eyelids and surrounding tissues, is most commonly associated with sinusitis. The anatomical proximity of the sinuses to the orbit makes it a frequent source of infection that can spread to the surrounding soft tissues, including the eyelids. In children, particularly, acute sinus infections, particularly in the maxillary or ethmoidal sinuses, can lead to periorbital cellulitis.

While otitis media, skin infections, and pharyngitis can also lead to various complications, they are less commonly the direct precursor to periorbital cellulitis compared to sinusitis. This connection underscores the importance of recognizing and effectively managing sinusitis, especially in pediatric populations where it is prevalent, to prevent the subsequent development of periorbital cellulitis and potential complications.

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