What is the primary treatment for Bullous pemphigoid?

Bullous pemphigoid is an autoimmune blistering disorder characterized by the formation of large blisters on the skin. The primary treatment involves the use of high-dose corticosteroids, which function to reduce inflammation and suppress the immune system’s overactive response that leads to the formation of blisters. These steroids, when administered in high doses, effectively mitigate the symptoms and promote healing by targeting the underlying autoimmune mechanism.

High-dose corticosteroids are particularly effective because they can quickly control the disease's activity and alleviate symptoms such as itching and skin discomfort. The treatment often involves an initial aggressive approach with a tapering strategy as the disease comes under control.

Other treatment options, while they may play supportive roles or be used in specific situations, are not the first-line approach. For instance, immunosuppressants can be beneficial, particularly for patients who cannot tolerate steroids or when the disease is resistant, but they are not the primary treatment. Antibiotics are generally not used in the treatment of bullous pemphigoid unless there is a secondary infection of the blisters. Topical ointments can sometimes be used to soothe the skin or in milder cases, but they do not address the underlying autoimmune process effectively compared to systemic corticosteroids. Thus, high