What is the typical duration of action for rapid-acting insulins?

Rapid-acting insulins are designed to quickly manage blood glucose levels following meals. The typical duration of action for these insulins is about 4 to 5 hours. This timeframe allows them to effectively cover postprandial glucose spikes, making them ideal for controlling blood sugar in response to carbohydrate intake.

Rapid-acting insulins, such as lispro, aspart, and glulisine, have a fast onset of action, usually starting to work within 15 minutes after injection. The peak activity occurs around 1 to 3 hours, which is when they are most effective at lowering glucose levels. After approximately 4 to 5 hours, these insulins are largely cleared from the system, reducing their effectiveness at controlling blood glucose levels.

Understanding the pharmacokinetics of quick-acting insulins is crucial in managing diabetes effectively, ensuring both blood sugar control and minimizing the risk of hypoglycemia following meals.