What laboratory finding is very elevated in patients with Polymyalgia rheumatica?

In patients with Polymyalgia Rheumatica, a very elevated erythrocyte sedimentation rate (ESR) is commonly observed. This finding is significant as it indicates the presence of systemic inflammation, which is characteristic of the condition. Polymyalgia Rheumatica primarily affects older adults and presents with symptoms such as muscle pain and stiffness, particularly in the shoulders and hips.

The elevation in ESR is due to the inflammatory processes occurring in the body; it reflects the activity of the disease rather than being a specific marker for it. A high ESR suggests ongoing inflammation and helps differentiate Polymyalgia Rheumatica from other conditions that may present with similar symptoms.

While other laboratory markers, such as CRP, may also be elevated in the context of inflammation, the ESR is particularly noted for its elevation in this condition. Hence, recognizing a very elevated ESR in these patients serves as an important diagnostic tool in confirming the presence of Polymyalgia Rheumatica.