What psychiatric symptoms may commonly occur in Cushing's disease?

Cushing's disease, caused by excessive cortisol production, can significantly affect an individual's mental health. One of the most common psychiatric symptoms associated with this condition is depression, which may manifest as a pervasive low mood, loss of interest in activities, and feelings of worthlessness. Additionally, psychosis can occur, characterized by delusions or hallucinations that are often related to the overwhelming stress and physiological changes brought about by elevated cortisol levels.

These psychiatric symptoms are especially linked to the impact of cortisol on the brain, including alterations in mood regulation and stress responses. Patients with Cushing's disease often experience a range of psychological disturbances due to the hormonal imbalances that occur, making depression and psychosis prominent symptoms in this context.

While anxiety and manic episodes, insomnia, fatigue, as well as memory loss and confusion can also be present in various contexts, they are not the hallmark psychiatric symptoms most commonly observed in Cushing's disease. Understanding the specific range of psychiatric manifestations associated with such endocrine disorders can aid in effective diagnosis and treatment.