What umbilical node is linked with gastric adenocarcinoma and ovarian cancer?

The Sister Mary Joseph nodule is a specific type of metastatic lesion that occurs in the umbilical region and is often associated with certain malignancies, particularly gastric adenocarcinoma and ovarian cancer. This nodule represents metastatic spread of cancerous cells to the umbilicus and is considered a significant clinical finding that can indicate advanced disease.

The name "Sister Mary Joseph nodule" originates from a surgical nurse who noted this association, emphasizing its clinical relevance. When evaluating patients for potential malignancies, the presence of a Sister Mary Joseph nodule can alert clinicians to investigate further for gastrointestinal or gynecological cancers.

Understanding the significance of this nodule in the clinical context is crucial for early diagnosis and management of cancers that can present in this way.