When does Non-Hodgkin's lymphoma typically present?

Non-Hodgkin's lymphoma (NHL) is known to have a higher incidence in older adults, particularly in the age group of 50 to 60 years. This type of lymphoma can present at various ages, but it is particularly associated with middle-aged and older adults. The risk factors for developing NHL include age, where the incidence significantly increases in older populations, and is more common in individuals aged 60 and older. The demographic trends indicate that the majority of cases fall within this age range, making it a critical aspect for clinicians to consider when evaluating symptoms.

Although it can occur in younger individuals, particularly in certain subtypes or in conditions such as primary mediastinal B-cell lymphoma, the majority of cases typically cluster around middle age to late adulthood. Therefore, identifying this age group as a point of focus for diagnosis and screening is important in clinical practice.