Which complication is associated with aortic root dilation in Marfan syndrome?

Aortic root dilation is a well-known cardiovascular complication associated with Marfan syndrome, a genetic disorder that affects connective tissue. This abnormal dilation of the aortic root can lead to various serious complications, one of which is an aortic aneurysm.

In Marfan syndrome, the connective tissue that provides structural support to the aorta is weakened, making it prone to enlargement and subsequent aneurysm formation. An aortic aneurysm occurs when there is a localized abnormal dilation of the aorta, which can eventually lead to rupture or dissection, both of which are life-threatening conditions. The association between aortic root dilation and aneurysm is a critical aspect of managing patients with Marfan syndrome, as regular monitoring and timely intervention can prevent severe outcomes.

While other complications like heart valve insufficiency, stroke, and arrhythmias may also occur in Marfan syndrome due to cardiovascular changes, the direct and primary complication linked to aortic root dilation is the development of an aortic aneurysm. This unique relationship is important for clinical assessment and treatment planning in affected individuals.