Which demographic is most affected by Brugada syndrome?

Brugada syndrome is a genetic disorder that significantly affects certain populations, particularly individuals of Asian descent. Studies have shown that Brugada syndrome is more prevalent in Southeast Asian countries, and research indicates that Asians, especially those from regions like Thailand, Japan, and Malaysia, have a higher frequency of the genetic mutations associated with this condition.

The syndrome is characterized by a specific pattern on the electrocardiogram (ECG) and can lead to life-threatening arrhythmias. While it can occur in individuals of any ethnic background, the increased incidence in Asian populations highlights the importance of genetic predisposition and raises awareness for screening in these demographics. Additionally, the condition tends to present more prominently in males than females, which supports the focus on certain demographic groups.

Thus, recognizing that Brugada syndrome predominantly affects Asian individuals aligns with current epidemiological data and understanding of the genetic factors contributing to the disease.