Which demographic is most likely to present with Chronic Lymphocytic Leukemia (CLL)?

Chronic Lymphocytic Leukemia (CLL) predominantly affects older adults, with a significant majority of cases identified in individuals aged 65 and older. This age group is particularly at risk due to the nature of CLL, which is thought to develop over a long period of time, often without any noticeable symptoms in the early stages. The condition is more prevalent in men compared to women, making this demographic profile consistent with the clinical observations and epidemiological data associated with CLL.

Considering other demographics, women in their 40s and children under 18 are less commonly diagnosed with CLL, as the disease typically manifests in older populations. Middle-aged adults might also develop CLL; however, the peak incidence is certainly more pronounced in older age groups, especially around 65 years old. Thus, the age and gender distribution of CLL risk aligns with the characteristics of men around 65 years as the most likely demographic to present with this type of leukemia.