Which demographic is most likely to be diagnosed with Systemic Lupus Erythematosus (SLE)?

Systemic Lupus Erythematosus (SLE) is an autoimmune disease that predominantly affects women, particularly those of childbearing age. Research indicates that African American women have a significantly higher prevalence of SLE compared to other demographics. This group is not only more likely to develop the disease but also tends to experience more severe symptoms and complications associated with lupus.

Factors contributing to this demographic's susceptibility include genetic, hormonal, and environmental influences. The combination of these factors plays a crucial role in the heightened risk among African American women in this age group, making them the most commonly diagnosed demographic for SLE.

Other demographics mentioned, while they may experience lupus, do not reflect the higher prevalence seen in African American women of childbearing age. For instance, SLE is less common in older individuals and in males. The nature of autoimmune diseases often shows a greater incidence and severity in populations that face unique socio-environmental challenges, further emphasizing the correct answer.