Which infection is lichen planus most commonly associated with?

Lichen planus is an inflammatory condition that presents as a rash and can affect various areas of the skin and mucous membranes. It is most commonly associated with Hepatitis C virus infection. Studies have demonstrated a notable prevalence of lichen planus among individuals with chronic Hepatitis C, suggesting a significant correlation between the two conditions.

The mechanism linking lichen planus and Hepatitis C is not fully understood, but it is believed that the immune response triggered by the virus may contribute to the dermatitis seen in lichen planus. Additionally, the clinical presentation of lichen planus in patients with Hepatitis C can sometimes be more severe or atypical.

Although lichen planus can be associated with other infections or conditions, the strongest and most consistent association is with Hepatitis C. This correlation highlights the importance of considering viral hepatitis in patients diagnosed with lichen planus, prompting further evaluation and management of liver health in these individuals.