Which lab results are typically associated with Sjogren's syndrome?

The association of positive rheumatoid factor and antinuclear antibodies (ANA) with Sjogren's syndrome is well-documented in clinical practice. Sjogren's syndrome is an autoimmune disorder that predominantly affects moisture-producing glands, leading to symptoms such as dry mouth and dry eyes.

The presence of rheumatoid factor, which is an antibody that is often found in various autoimmune diseases, indicates an autoimmune process. Additionally, a positive ANA test suggests the presence of autoantibodies that can indicate a range of autoimmune conditions, including Sjogren's syndrome. In many patients with this condition, these lab findings are commonly observed, which helps in diagnosing the disorder.

Other options present various lab results that do not specifically correlate with Sjogren's syndrome. For instance, high cholesterol and blood glucose levels may indicate metabolic conditions rather than autoimmune disorders. Low hemoglobin and elevated liver enzymes might suggest a different set of pathologies, and negative leukocytes with a low platelet count do not provide the typical laboratory profile associated with this syndrome.

Therefore, the combination of positive rheumatoid factor and ANA is a hallmark in identifying patients who may have Sjogren's syndrome, underscoring why this answer is the correct choice.