Which of the following diseases is NOT caused by H. Pylori?

Cirrhosis is not caused by H. pylori infection. H. pylori, or Helicobacter pylori, is a type of bacteria that is primarily associated with gastric diseases. It is known to play a significant role in the development of peptic ulcers, which are sores that develop on the lining of the stomach or the first part of the small intestine, due to the bacteria's ability to disrupt the protective mucous layer.

Additionally, H. pylori is linked to gastric adenocarcinoma, as chronic infection with this bacterium can lead to changes in the stomach lining, which increases the risk of developing cancer.

Gastroesophageal reflux disease (GERD) is primarily related to issues with the lower esophageal sphincter and the motility of the esophagus, rather than H. pylori. However, it is still important to note that the bacteria does not have a direct causative relationship with cirrhosis of the liver, which is typically caused by factors such as chronic alcohol abuse, viral hepatitis, or other chronic liver diseases.

Therefore, cirrhosis stands out as the condition not related to H. pylori infection.