Which symptom is NOT associated with nephrotic syndrome?

In nephrotic syndrome, the primary features typically include significant proteinuria, which is the excessive loss of protein in the urine, often leading to low levels of protein in the blood. This condition can also cause edema, as a result of low oncotic pressure secondary to protein loss. Ascites may develop due to fluid retention from the body's compensatory mechanisms for low blood volume.

Orthostatic hypotension can occur in some cases, particularly if a patient becomes volume-depleted as a consequence of protein loss or other factors. However, this is not a defining symptom of nephrotic syndrome.

Increased urination, on the other hand, is not typically associated with nephrotic syndrome. Patients often experience reduced urine output or changes in urination patterns related to edema and fluid retention, rather than increased urination. The syndrome primarily characterizes itself by the conditions I mentioned earlier, focusing on protein loss and fluid retention rather than an increase in urination frequency.