Which two disease states are commonly linked to Campylobacter infection?

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Campylobacter infection is primarily associated with gastrointestinal illness, but it can also lead to other serious complications. The link to Guillain-Barré syndrome, an acute autoimmune condition that can cause muscle weakness and paralysis, is particularly notable. This association arises because the body's immune response to the Campylobacter bacteria can mistakenly target peripheral nerves, resulting in the symptoms characteristic of Guillain-Barré syndrome.

Similarly, Campylobacter infection can trigger reactive arthritis, which is a form of joint inflammation that occurs as a reaction to an infection in another part of the body. This condition commonly affects the knees, ankles, and feet and can follow an episode of gastroenteritis caused by Campylobacter.

Understanding these associations highlights the complexities of infections and their potential long-term effects on health, particularly regarding autoimmune responses. The other options do not have well-established connections to Campylobacter infection, focusing instead on other conditions or diseases that either involve different pathogenic mechanisms or are not linked to the consequences of Campylobacter.

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