Which two syndromes cause amenorrhea in women with normal estrogen levels?

The correct answer identifies Polycystic Ovarian Syndrome (PCOS) and Asherman's Syndrome as conditions that can lead to amenorrhea while maintaining normal estrogen levels in women.

In PCOS, women typically have hormonal imbalances that can result in irregular menstrual cycles or amenorrhea due to the presence of multiple cysts on the ovaries and increased androgen levels. However, despite these hormonal irregularities, estrogen levels can remain normal, allowing women to experience amenorrhea without the typical associated low estrogen levels seen in other conditions.

Asherman's Syndrome, characterized by intrauterine adhesions, can lead to amenorrhea by preventing normal menstrual flow, but estrogen levels may remain within the normal range because the ovaries are still capable of producing this hormone. The absence of menstrual bleeding is due to the structural changes in the uterus rather than a deficiency in estrogen.

This distinction highlights how both syndromes disrupt normal menstrual function despite the presence of adequate estrogen, leading to amenorrhea.