Who is most likely to have Hemophilia A?

Hemophilia A is an X-linked recessive genetic disorder that primarily affects males. This is due to the fact that the gene responsible for producing clotting factor VIII is located on the X chromosome. Males have one X and one Y chromosome (XY), while females have two X chromosomes (XX). Since males have only one copy of the X chromosome, if they inherit the mutated gene, they will express the condition. Females, on the other hand, have a second X chromosome that can often compensate for the defective one, meaning they are typically carriers rather than affected.

Thus, while females can inherit the gene and pass it on, males are disproportionately affected, making them the population most likely to have Hemophilia A. The other answer choices do not accurately represent the risk and prevalence of Hemophilia A, as the condition is not specific to children or evenly distributed across all age groups; it predominantly affects men.